![]() Be sure your caregivers know ahead of time that you are using this medicine.Ĭongestive heart failure or other heart problems If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking metformin and pioglitazone. Metabolic acidosis or ketoacidosis (call your doctor for treatment). You should not use this medicine if you are allergic to metformin or pioglitazone, or if you have: You may report side effects to FDA at 1-80. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Low red blood cells (anemia)-pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.Ĭommon side effects of metformin and pioglitazone may include:Ĭold symptoms such as stuffy nose, sinus pain, sneezing, sore throat. Liver problems-loss of appetite, nausea, vomiting, stomach pain, tiredness, dark urine, jaundice (yellowing of the skin or eyes) or Heart problems- swelling, rapid weight gain, feeling short of breath Pink or red urine, painful or difficult urination, new or worsening urge to urinate Metformin and pioglitazone may cause serious side effects. Get emergency medical help if you have even mild symptoms such as:įeeling dizzy, light-headed, tired, or very weak Some people using metformin and pioglitazone develop lactic acidosis, which can be fatal. ![]() ![]() Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.
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